منابع مشابه
The protection of the myocardium by amifostine against mitoxantrone-induced acute cardiotoxicity in rats.
OBJECTIVE Amifostine (AMI) has been used for the prevention of doxorubicin-induced cardiotoxicity in several experimental and a few clinical studies. The aim of this study was to investigate the effects of AMI on lipid peroxidation, protective enzymes, and mitoxantrone (MITO)-induced acute cardiotoxicity in the rat heart using biochemical tests and histopathological examinations. METHODS Thir...
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Until 20 years ago, it was thought that atrial and ventricular fibrillation were highly disorganized, with tens or hundreds of tiny wandering wavelets simultaneously present and following ever-changing pathways.1 In this model, the disorganization is due to intrinsic heterogeneity of refractory periods that causes transitory islets of refractoriness about which wavelets circulate. However, abou...
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Correspondence to: Dr James H McGowan, Cardiothoracic Unit, James Cook University Hospital, Middlesbrough TS5 3BW, UK; jamesmcgowan@ blueyonder.co.uk . . . . . . . . . . . . . . . . . . . . . . . T he assessment of risk, and its subsequent manipulation, accounts for a large amount of what we do in cardiology. Among the heart failure population, increasing numbers of tools are being utilised for...
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The vascular endothelium releases a diffusible factor that hyperpolarizes and hence relaxes vascular smooth muscle cells predominantly through activation of Ca(2+)-dependent K(+) channels. In the coronary circulation, this endothelium-derived hyperpolarizing factor appears to be a cytochrome P(450)-derived arachidonic acid epoxide, the release of which may play a crucial role in the maintenance...
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matory cytokines downstream of the donor T cell.4 The mechanisms by which T cells are activated during allogeneic transplantation and their subsequent enhancement of host APC allostimulatory capacity will be important avenues for future study. From a clinical perspective, the current study suggests a novel approach to GVHD prophylaxis: the specific deletion of recipient T cells prior to transpl...
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ژورنال
عنوان ژورنال: Cureus
سال: 2018
ISSN: 2168-8184
DOI: 10.7759/cureus.2994